Anti-PDS5A antibody (STJA0009683)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PDS5A
General Information
| Short Description | Rabbit polyclonal anti-Sister chromatid cohesion protein PDS5 homolog A for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDS5A |
| Gene ID | 23244 |
| Uniprot ID | PDS5A_HUMAN |
| Immunogen | Synthesized peptide derived from human PDS5A |
| Specificity | This antibody detects endogenous levels of PDS5A at Human, Rat |
Additional Info
| Function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. |
| Protein Name | Sister Chromatid Cohesion Protein Pds5 Homolog ACell Proliferation-Inducing Gene 54 ProteinSister Chromatid Cohesion Protein 112Scc-112 |
| Database Links | Reactome: R-HSA-2467813Reactome: R-HSA-2468052Reactome: R-HSA-2470946Reactome: R-HSA-2500257 |
| Cellular Localisation | NucleusAssociated With Chromatin Through Most Of The Cell CycleDissociates From Chromatin In Late ProphaseReassociates During Late Telophase |
| Alternative Antibody Names | Anti-Sister Chromatid Cohesion Protein Pds5 Homolog A antibodyAnti-Cell Proliferation-Inducing Gene 54 Protein antibodyAnti-Sister Chromatid Cohesion Protein 112 antibodyAnti-Scc-112 antibodyAnti-PDS5A antibodyAnti-KIAA0648 antibodyAnti-PDS5 antibodyAnti-PIG54 antibody |
Information sourced from Uniprot.org