Anti-PDLIM7 antibody (STJA0006925)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PDLIM7
General Information
| Short Description | Rabbit polyclonal anti-PDZ and LIM domain protein 7 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDLIM7 |
| Gene ID | 9260 |
| Uniprot ID | PDLI7_HUMAN |
| Immunogen | Synthesized peptide derived from human PDLIM7 |
| Specificity | This antibody detects endogenous levels of PDLIM7 at Human, Mouse, Rat |
Additional Info
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway. |
| Protein Name | Pdz And Lim Domain Protein 7Lim Mineralization ProteinLmpProtein Enigma |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | CytoplasmCytoskeletonColocalizes With Ret To The Cell Periphery And In Some Cytoskeletal ComponentsColocalizes With Tpm2 Near The Z Line In MuscleColocalizes With Tbx4 And Tbx5 To Actin Filaments |
| Alternative Antibody Names | Anti-Pdz And Lim Domain Protein 7 antibodyAnti-Lim Mineralization Protein antibodyAnti-Lmp antibodyAnti-Protein Enigma antibodyAnti-PDLIM7 antibodyAnti-ENIGMA antibody |
Information sourced from Uniprot.org