| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-PDZ and LIM domain protein 7 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDLIM7 |
| Gene ID: | 9260 |
| Uniprot ID: | PDLI7_HUMAN |
| Specificity: | This antibody detects endogenous levels of PDLIM7 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human PDLIM7 |
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway. |
| Protein Name | Pdz And Lim Domain Protein 7 Lim Mineralization Protein Lmp Protein Enigma |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | Cytoplasm Cytoskeleton Colocalizes With Ret To The Cell Periphery And In Some Cytoskeletal Components Colocalizes With Tpm2 Near The Z Line In Muscle Colocalizes With Tbx4 And Tbx5 To Actin Filaments |
| Alternative Antibody Names | Anti-Pdz And Lim Domain Protein 7 antibody Anti-Lim Mineralization Protein antibody Anti-Lmp antibody Anti-Protein Enigma antibody Anti-PDLIM7 antibody Anti-ENIGMA antibody |
Information sourced from Uniprot.org