| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dual specificity calcium/calmodulin-dependent 3 NA, 5 cyclic nucleotide phosphodiesterase 1C (148-198) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDE1C |
| Gene ID: |
5137 |
| Uniprot ID: |
PDE1C_HUMAN |
| Immunogen Region: |
148-198 |
| Specificity: |
This antibody detects endogenous levels of human PDE1C |
| Immunogen: |
Synthesized peptide derived from human PDE1C AA range: 148-198 |
| Function | Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB (Probable). |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1cCam-Pde 1cHcam3 |
| Database Links | Reactome: R-HSA-111957 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c antibodyAnti-Cam-Pde 1c antibodyAnti-Hcam3 antibodyAnti-PDE1C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
