Anti-PDE1C antibody (148-198) (STJA0006516)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PDE1C AA range: 148-198
General Information
| Short Description | Rabbit polyclonal anti-Dual specificity calcium/calmodulin-dependent 3 NA, 5 cyclic nucleotide phosphodiesterase 1C (148-198) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE1C |
| Gene ID | 5137 |
| Uniprot ID | PDE1C_HUMAN |
| Immunogen | Synthesized peptide derived from human PDE1C AA range: 148-198 |
| Immunogen Region | 148-198 |
| Specificity | This antibody detects endogenous levels of human PDE1C |
Additional Info
| Function | Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB (Probable). |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1cCam-Pde 1cHcam3 |
| Database Links | Reactome: R-HSA-111957 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c antibodyAnti-Cam-Pde 1c antibodyAnti-Hcam3 antibodyAnti-PDE1C antibody |
Information sourced from Uniprot.org