| Short Description : | Goat polyclonal antibody anti-PDE1A (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 55kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 62.3kDa according to NP_005010.2). Recommended concentration: 1-3µg/ml. Primary incubation was 1 hour.< |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PDE1A |
| Gene ID: | 5136 |
| Uniprot ID: | PDE1A_HUMAN |
| Accession Number: | NP_005010.2 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | DLHKNSEDLVNAE |
| Specificity: | This antibody is expected to recognize isoform 1 (NP_005010.2) only. |
| Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1aCam-Pde 1a61 Kda Cam-PdeHcam-1 |
| Database Links | Reactome: R-HSA-111957Reactome: R-HSA-418457Reactome: R-HSA-418555 |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1a antibodyAnti-Cam-Pde 1a antibodyAnti-61 Kda Cam-Pde antibodyAnti-Hcam-1 antibodyAnti-PDE1A antibody |
Information sourced from Uniprot.org
