Anti-PDE1A antibody (C-Term) (STJ72122)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PDE1A (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 55kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 62.3kDa according to NP_005010.2). Recommended concentration: 1-3µg/ml. Primary incubation was 1 hour.< |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE1A |
| Gene ID | 5136 |
| Uniprot ID | PDE1A_HUMAN |
| Accession Number | NP_005010.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | DLHKNSEDLVNAE |
| Specificity | This antibody is expected to recognize isoform 1 (NP_005010.2) only. |
Additional Info
| Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1aCam-Pde 1a61 Kda Cam-PdeHcam-1 |
| Database Links | Reactome: R-HSA-111957Reactome: R-HSA-418457Reactome: R-HSA-418555 |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1a antibodyAnti-Cam-Pde 1a antibodyAnti-61 Kda Cam-Pde antibodyAnti-Hcam-1 antibodyAnti-PDE1A antibody |
Information sourced from Uniprot.org