| Short Description : | Rabbit polyclonal PDC (1-246) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDC |
| Gene ID: | 5132 |
| Uniprot ID: | PHOS_HUMAN |
| Immunogen Region: | 1-246 |
| Immunogen Sequence: | MEEAKSQSLEEDFEGQATHT GPKGVINDWRKFKLESQDSD SIPPSKKEILRQMSSPQSRN GKDSKERVSRKMSIQEYELI HKEKEDENCLRKYRRQCMQD MHQKLSFGPRYGFVYELETG KQFLETIEKELKITTIVVHI YEDGIKGCDALNSSLTCLAA EYPIVKFCKIKASNTGAGDR FSLDVLPTLLIYKGGELISN FISVAEQFAEEFFAGDVESF LNEYGLLPEREVHVLEHTK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_002588.3). |
| Post Translational Modifications | Light-induced changes in cyclic nucleotide levels modulate the phosphorylation of this protein by cAMP kinase. |
| Function | May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. |
| Protein Name | PhosducinPhd33 Kda Phototransducing ProteinProtein Meka |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleusCell ProjectionCiliumPhotoreceptor Outer SegmentPhotoreceptor Inner SegmentIsoform 2: Nucleus |
| Alternative Antibody Names | Anti-Phosducin antibodyAnti-Phd antibodyAnti-33 Kda Phototransducing Protein antibodyAnti-Protein Meka antibodyAnti-PDC antibody |
Information sourced from Uniprot.org
