Immunofluorescence analysis of MCF7 cells using PCBD1 antibody (STJ28475). Blue: DAPI for nuclear staining.

Anti-PCBD1 antibody (1-104) (STJ28475)

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STJ28475
€140.63 - €655.63
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:10-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PCBD1
Gene ID: 5092
Uniprot ID: PHS_HUMAN
Immunogen Region: 1-104
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272.1).
Immunogen Sequence: MAGKAHRLSAEERDQLLPNL RAVGWNELEGRDAIFKQFHF KDFNRAFGFMTRVALQAEKL DHHPEWFNVYNKVHITLSTH ECAGLSERDINLASFIEQVA VSMT
Function Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription.
Protein Name Pterin-4-Alpha-Carbinolamine Dehydratase
Phs
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase
Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha
Dcoh
Dimerization Cofactor Of Hnf1
Phenylalanine Hydroxylase-Stimulating Protein
Pterin Carbinolamine Dehydratase
Pcd
Database Links Reactome: R-HSA-8964208
Cellular Localisation Cytoplasm
Nucleus
Recruited To The Nucleus Through The Interaction With Hnf1b
Alternative Antibody Names Anti-Pterin-4-Alpha-Carbinolamine Dehydratase antibody
Anti-Phs antibody
Anti-4-Alpha-Hydroxy-Tetrahydropterin Dehydratase antibody
Anti-Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha antibody
Anti-Dcoh antibody
Anti-Dimerization Cofactor Of Hnf1 antibody
Anti-Phenylalanine Hydroxylase-Stimulating Protein antibody
Anti-Pterin Carbinolamine Dehydratase antibody
Anti-Pcd antibody
Anti-PCBD1 antibody
Anti-DCOH antibody
Anti-PCBD antibody

Information sourced from Uniprot.org

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