Immunofluorescence analysis of MCF7 cells using PCBD1 antibody (STJ28475). Blue: DAPI for nuclear staining.

Anti-PCBD1 antibody (1-104) (STJ28475)

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STJ28475
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Short Description :Rabbit polyclonal PCBD1 (1-104) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:10-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:PCBD1
Gene ID:5092
Uniprot ID:PHS_HUMAN
Immunogen Region:1-104
Immunogen Sequence:MAGKAHRLSAEERDQLLPNL RAVGWNELEGRDAIFKQFHF KDFNRAFGFMTRVALQAEKL DHHPEWFNVYNKVHITLSTH ECAGLSERDINLASFIEQVA VSMT
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272.1).
Function Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription.
Protein Name Pterin-4-Alpha-Carbinolamine Dehydratase
Phs
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase
Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha
Dcoh
Dimerization Cofactor Of Hnf1
Phenylalanine Hydroxylase-Stimulating Protein
Pterin Carbinolamine Dehydratase
Pcd
Database Links Reactome: R-HSA-8964208
Cellular Localisation Cytoplasm
Nucleus
Recruited To The Nucleus Through The Interaction With Hnf1b
Alternative Antibody Names Anti-Pterin-4-Alpha-Carbinolamine Dehydratase antibody
Anti-Phs antibody
Anti-4-Alpha-Hydroxy-Tetrahydropterin Dehydratase antibody
Anti-Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha antibody
Anti-Dcoh antibody
Anti-Dimerization Cofactor Of Hnf1 antibody
Anti-Phenylalanine Hydroxylase-Stimulating Protein antibody
Anti-Pterin Carbinolamine Dehydratase antibody
Anti-Pcd antibody
Anti-PCBD1 antibody
Anti-DCOH antibody
Anti-PCBD antibody

Information sourced from Uniprot.org

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