| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PCBD1 (1-104) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PCBD1 |
| Gene ID: |
5092 |
| Uniprot ID: |
PHS_HUMAN |
| Immunogen Region: |
1-104 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272.1). |
| Immunogen Sequence: |
MAGKAHRLSAEERDQLLPNL RAVGWNELEGRDAIFKQFHF KDFNRAFGFMTRVALQAEKL DHHPEWFNVYNKVHITLSTH ECAGLSERDINLASFIEQVA VSMT |
| Function | Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription. |
| Protein Name | Pterin-4-Alpha-Carbinolamine DehydratasePhs4-Alpha-Hydroxy-Tetrahydropterin DehydrataseDimerization Cofactor Of Hepatocyte Nuclear Factor 1-AlphaDcohDimerization Cofactor Of Hnf1Phenylalanine Hydroxylase-Stimulating ProteinPterin Carbinolamine DehydratasePcd |
| Database Links | Reactome: R-HSA-8964208 |
| Cellular Localisation | CytoplasmNucleusRecruited To The Nucleus Through The Interaction With Hnf1b |
| Alternative Antibody Names | Anti-Pterin-4-Alpha-Carbinolamine Dehydratase antibodyAnti-Phs antibodyAnti-4-Alpha-Hydroxy-Tetrahydropterin Dehydratase antibodyAnti-Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha antibodyAnti-Dcoh antibodyAnti-Dimerization Cofactor Of Hnf1 antibodyAnti-Phenylalanine Hydroxylase-Stimulating Protein antibodyAnti-Pterin Carbinolamine Dehydratase antibodyAnti-Pcd antibodyAnti-PCBD1 antibodyAnti-DCOH antibodyAnti-PCBD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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