Anti-PCBD1 antibody [R41-2R-5] (STJA0035589)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PCBD1
General Information
| Short Description | Rabbit monoclonal anti-PCBD1 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R41-2R-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PCBD1 |
| Gene ID | 5092 |
| Uniprot ID | PHS_HUMAN |
| Immunogen | A synthesized peptide derived from human PCBD1 |
Additional Info
| Function | Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription. |
| Protein Name | Pterin-4-Alpha-Carbinolamine DehydratasePhs4-Alpha-Hydroxy-Tetrahydropterin DehydrataseDimerization Cofactor Of Hepatocyte Nuclear Factor 1-AlphaDcohDimerization Cofactor Of Hnf1Phenylalanine Hydroxylase-Stimulating ProteinPterin Carbinolamine DehydratasePcd |
| Database Links | Reactome: R-HSA-8964208 |
| Cellular Localisation | CytoplasmNucleusRecruited To The Nucleus Through The Interaction With Hnf1b |
| Alternative Antibody Names | Anti-Pterin-4-Alpha-Carbinolamine Dehydratase antibodyAnti-Phs antibodyAnti-4-Alpha-Hydroxy-Tetrahydropterin Dehydratase antibodyAnti-Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha antibodyAnti-Dcoh antibodyAnti-Dimerization Cofactor Of Hnf1 antibodyAnti-Phenylalanine Hydroxylase-Stimulating Protein antibodyAnti-Pterin Carbinolamine Dehydratase antibodyAnti-Pcd antibodyAnti-PCBD1 antibodyAnti-DCOH antibodyAnti-PCBD antibody |
Information sourced from Uniprot.org