| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/IP |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DBI (1-104) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200IF/ICC 1:50-1:200IP 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DBI |
| Gene ID: |
1622 |
| Uniprot ID: |
ACBP_HUMAN |
| Immunogen Region: |
1-104 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human DBI (NP_001171513.1). |
| Immunogen Sequence: |
MWGDLWLLPPASANPGTGTE AEFEKAAEEVRHLKTKPSDE EMLFIYGHYKQATVGDINTE RPGMLDFTGKAKWDAWNELK GTSKEDAMKAYINKVEELKK KYGI |
| Tissue Specificity | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
| Function | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
| Protein Name | Acyl-Coa-Binding ProteinAcbpDiazepam-Binding InhibitorDbiEndozepineEp |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusGolgi Localization Is Dependent On Ligand Binding |
| Alternative Antibody Names | Anti-Acyl-Coa-Binding Protein antibodyAnti-Acbp antibodyAnti-Diazepam-Binding Inhibitor antibodyAnti-Dbi antibodyAnti-Endozepine antibodyAnti-Ep antibodyAnti-DBI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunoprecipitation of DBI in 300 µg extracts from HeLa cells using 3 µg [KO Validated] DBI Rabbit polyclonal antibody (STJ119997). Western blot analysis was performed using [KO Validated] DBI Rabbit polyclonal antibody (STJ119997) at 1:1000 dilution.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98782/382831/STJ119997_1__34510.1713151335.jpg?c=1 "Immunoprecipitation of DBI in 300 µg extracts from HeLa cells using 3 µg [KO Validated] DBI Rabbit polyclonal antibody (STJ119997). Western blot analysis was performed using [KO Validated] DBI Rabbit polyclonal antibody (STJ119997) at 1:1000 dilution.")
