Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-PACSIN3 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:4000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
PACSIN3 |
Gene ID: |
29763 |
Uniprot ID: |
PACN3_HUMAN |
Immunogen Region: |
N-Term |
Accession Number: |
NP_057307.2 |
Immunogen Sequence: |
APEEDAGGEALGGS |
Post Translational Modifications | Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). |
Function | Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity. |
Protein Name | Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3Sh3 Domain-Containing Protein 6511 |
Database Links | Reactome: R-HSA-8856828 |
Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideDetected At The Inner Aspect Of The Plasma Membrane In Myotubes |
Alternative Antibody Names | Anti-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 antibodyAnti-Sh3 Domain-Containing Protein 6511 antibodyAnti-PACSIN3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance