• STJ70100 staining (1µg/ml) of H460 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-PACSIN3 antibody (N-Term) (STJ70100)

SKU:
STJ70100-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PACSIN3 (N-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PACSIN3
Gene ID: 29763
Uniprot ID: PACN3_HUMAN
Immunogen Region: N-Term
Accession Number: NP_057307.2
Immunogen Sequence: APEEDAGGEALGGS
Post Translational Modifications Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Protein Name Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3
Sh3 Domain-Containing Protein 6511
Database Links Reactome: R-HSA-8856828
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected At The Inner Aspect Of The Plasma Membrane In Myotubes
Alternative Antibody Names Anti-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 antibody
Anti-Sh3 Domain-Containing Protein 6511 antibody
Anti-PACSIN3 antibody

Information sourced from Uniprot.org

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