Anti-PABPC4 antibody (350-450) (STJ27744)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PABPC4 (350-450) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PABPC4 |
| Gene ID | 8761 |
| Uniprot ID | PABP4_HUMAN |
| Immunogen Region | 350-450 |
| Immunogen Sequence | VTEMNGRIVGSKPLYVALAQ RKEERKAHLTNQYMQRVAGM RALPANAILNQFQPAAGGYF VPAVPQAQGRPPYYTPNQLA QMRPNPRWQQGGRPQGFQGM P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC4 (NP_003810.1). |
Additional Info
| Tissue Specificity | Expressed at low levels in resting normal T cells.following T-cell activation, however, mRNA levels are rapidly up-regulated. |
| Post Translational Modifications | Arg-518 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | Binds the poly(A) tail of mRNA. Binds to SMIM26 mRNA and plays a role in its post-transcriptional regulation. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. |
| Protein Name | Polyadenylate-Binding Protein 4Pabp-4Poly(A-Binding Protein 4Activated-Platelet Protein 1App-1Inducible Poly(A-Binding ProteinIpabp |
| Database Links | |
| Cellular Localisation | CytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
| Alternative Antibody Names | Anti-Polyadenylate-Binding Protein 4 antibodyAnti-Pabp-4 antibodyAnti-Poly(A-Binding Protein 4 antibodyAnti-Activated-Platelet Protein 1 antibodyAnti-App-1 antibodyAnti-Inducible Poly(A-Binding Protein antibodyAnti-Ipabp antibodyAnti-PABPC4 antibodyAnti-APP1 antibodyAnti-PABP4 antibody |
Information sourced from Uniprot.org