Anti-PABPC4 antibody (350-450) (STJ27744)

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STJ27744
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Applications:WB/IHC-P/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:PABPC4
Gene ID:8761
Uniprot ID:PABP4_HUMAN
Immunogen Region:350-450
Immunogen Sequence:VTEMNGRIVGSKPLYVALAQ RKEERKAHLTNQYMQRVAGM RALPANAILNQFQPAAGGYF VPAVPQAQGRPPYYTPNQLA QMRPNPRWQQGGRPQGFQGM P
Specificity:A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC4 (NP_003810.1).
Tissue Specificity Expressed at low levels in resting normal T cells.following T-cell activation, however, mRNA levels are rapidly up-regulated.
Post Translational Modifications Arg-518 is dimethylated, probably to asymmetric dimethylarginine.
Function Binds the poly(A) tail of mRNA. Binds to SMIM26 mRNA and plays a role in its post-transcriptional regulation. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
Protein Name Polyadenylate-Binding Protein 4
Pabp-4
Poly(A-Binding Protein 4
Activated-Platelet Protein 1
App-1
Inducible Poly(A-Binding Protein
Ipabp
Database Links
Cellular Localisation Cytoplasm
Localized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas
Alternative Antibody Names Anti-Polyadenylate-Binding Protein 4 antibody
Anti-Pabp-4 antibody
Anti-Poly(A-Binding Protein 4 antibody
Anti-Activated-Platelet Protein 1 antibody
Anti-App-1 antibody
Anti-Inducible Poly(A-Binding Protein antibody
Anti-Ipabp antibody
Anti-PABPC4 antibody
Anti-APP1 antibody
Anti-PABP4 antibody

Information sourced from Uniprot.org