Anti-P3H1 antibody (STJA0008633)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human P3H1
General Information
| Short Description | Rabbit polyclonal anti-Prolyl 3-hydroxylase 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | P3H1 |
| Gene ID | 64175 |
| Uniprot ID | P3H1_HUMAN |
| Immunogen | Synthesized peptide derived from human P3H1 |
| Specificity | This antibody detects endogenous levels of P3H1 at Human, Mouse, Rat |
Additional Info
| Function | Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. |
| Protein Name | Prolyl 3-Hydroxylase 1Growth Suppressor 1Leucine- And Proline-Enriched Proteoglycan 1Leprecan-1 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Isoform 1: Endoplasmic ReticulumSecretedExtracellular SpaceExtracellular MatrixSecreted Into The Extracellular Matrix As A Chondroitin Sulfate Proteoglycan (Cspg) |
| Alternative Antibody Names | Anti-Prolyl 3-Hydroxylase 1 antibodyAnti-Growth Suppressor 1 antibodyAnti-Leucine- And Proline-Enriched Proteoglycan 1 antibodyAnti-Leprecan-1 antibodyAnti-P3H1 antibodyAnti-GROS1 antibodyAnti-LEPRE1 antibodyAnti-PSEC0109 antibody |
Information sourced from Uniprot.org