| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Prolyl 3-hydroxylase 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | P3H1 |
| Gene ID: | 64175 |
| Uniprot ID: | P3H1_HUMAN |
| Specificity: | This antibody detects endogenous levels of P3H1 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human P3H1 |
| Function | Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. |
| Protein Name | Prolyl 3-Hydroxylase 1Growth Suppressor 1Leucine- And Proline-Enriched Proteoglycan 1Leprecan-1 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Isoform 1: Endoplasmic ReticulumSecretedExtracellular SpaceExtracellular MatrixSecreted Into The Extracellular Matrix As A Chondroitin Sulfate Proteoglycan (Cspg) |
| Alternative Antibody Names | Anti-Prolyl 3-Hydroxylase 1 antibodyAnti-Growth Suppressor 1 antibodyAnti-Leucine- And Proline-Enriched Proteoglycan 1 antibodyAnti-Leprecan-1 antibodyAnti-P3H1 antibodyAnti-GROS1 antibodyAnti-LEPRE1 antibodyAnti-PSEC0109 antibody |
Information sourced from Uniprot.org
