Anti-P2RY4 antibody (4th Cytoplasmic Domain) (STJ13101609)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the 4th cytoplasmic domain of mouse P2Y4 (P2RY4) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-P2RY4 (4th Cytoplasmic Domain) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | P2ry4 |
| Gene ID | 57385 |
| Uniprot ID | P2RY4_MOUSE |
| Immunogen | A synthetic peptide from the 4th cytoplasmic domain of mouse P2Y4 (P2RY4) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 4th Cytoplasmic Domain |
| Specificity | Specific for P2RY4. |
Additional Info
| Post Translational Modifications | Phosphorylation of Ser-329 and Ser-330 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium-activated kinases. |
| Function | Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Name | P2y Purinoceptor 4P2y4 |
| Database Links | Reactome: R-MMU-417957Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 4 antibodyAnti-P2y4 antibodyAnti-P2ry4 antibodyAnti-P2y4r antibody |
Information sourced from Uniprot.org