Anti-P2RX5 antibody (340-390 aa) (STJ13101587)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 340-390 of human P2RX5 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-P2RX5 (340-390 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | P2RX5 |
| Gene ID | 5026 |
| Uniprot ID | P2RX5_HUMAN |
| Immunogen | A synthetic peptide from aa region 340-390 of human P2RX5 conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | 340-390 aa |
| Specificity | Specific for P2RX5. |
Additional Info
| Function | Isoform 6: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Unlike other P2RX receptors, the P2X5 receptor is also permeable to chloride. May play a supporting role in the inflammatory response. Isoform 1: Non-functional. |
| Protein Name | P2x Purinoceptor 5P2x5Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Isoform 6: Cell MembraneMulti-Pass Membrane ProteinThe Absence Of The Exon 10-Encoded Amino Acids Substantially Results In Subunit Aggregation And Retention In The Cell Cytoplasm |
| Alternative Antibody Names | Anti-P2x Purinoceptor 5 antibodyAnti-P2x5 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX5 antibodyAnti-P2X5 antibodyAnti-P2X5FL antibody |
Information sourced from Uniprot.org