| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-P2RX5 (340-390 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | P2RX5 |
| Gene ID: | 5026 |
| Uniprot ID: | P2RX5_HUMAN |
| Immunogen Region: | 340-390 aa |
| Specificity: | Specific for P2RX5. |
| Immunogen: | A synthetic peptide from aa region 340-390 of human P2RX5 conjugated to blue carrier protein was used as the antigen. |
| Function | Isoform 6: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Unlike, other P2RX receptors, the P2X5 receptor is also permeable to chloride. May play a supporting role in the inflammatory response. Isoform 1: Non-functional. |
| Protein Name | P2x Purinoceptor 5P2x5Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Isoform 6: Cell MembraneMulti-Pass Membrane ProteinThe Absence Of The Exon 10-Encoded Amino Acids Substantially Results In Subunit Aggregation And Retention In The Cell Cytoplasm |
| Alternative Antibody Names | Anti-P2x Purinoceptor 5 antibodyAnti-P2x5 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX5 antibodyAnti-P2X5 antibodyAnti-P2X5FL antibody |
Information sourced from Uniprot.org
