Anti-OSBPL1A antibody (937-950 aa) [R02-2E2] (STJA0011720)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human ORP1
General Information
| Short Description | Rabbit monoclonal anti-ORP1 (937-950 aa) for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-2E2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | OSBPL1A |
| Gene ID | 114876 |
| Uniprot ID | OSBL1_HUMAN |
| Immunogen | A synthetic peptide of human ORP1 |
| Immunogen Region | 937-950 aa |
Additional Info
| Function | Binds phospholipids.exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 1Orp-1Osbp-Related Protein 1 |
| Database Links | Reactome: R-HSA-192105Reactome: R-HSA-2132295 |
| Cellular Localisation | Late EndosomeColocalizes With Rab7aRab9a And Lamp1 In Late Endosomes |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 1 antibodyAnti-Orp-1 antibodyAnti-Osbp-Related Protein 1 antibodyAnti-OSBPL1A antibodyAnti-ORP1 antibodyAnti-OSBP8 antibodyAnti-OSBPL1 antibodyAnti-OSBPL1B antibody |
Information sourced from Uniprot.org