| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ORC3L (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 75kDa band observed in lysates of cell lines HepG2 and HeLa (calculated MW of 82.3kDa according to NP_862820.1 and NP_036513.2). Recommended concentration: 1-3µg/ml.An additiona |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ORC3 |
| Gene ID: |
23595 |
| Uniprot ID: |
ORC3_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_862820.1; NP_036513.2; NP_001184188.1 |
| Specificity: |
This antibody is expected to recognize reported isoforms NP_862820.1, NP_036513.2 and NP_001184188.1. |
| Immunogen Sequence: |
QKTDHVARLTWGGC |
| Function | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. |
| Protein Name | Origin Recognition Complex Subunit 3Origin Recognition Complex Subunit Latheo |
| Database Links | Reactome: R-HSA-113507Reactome: R-HSA-176187Reactome: R-HSA-68616Reactome: R-HSA-68689Reactome: R-HSA-68867Reactome: R-HSA-68949Reactome: R-HSA-68962 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Origin Recognition Complex Subunit 3 antibodyAnti-Origin Recognition Complex Subunit Latheo antibodyAnti-ORC3 antibodyAnti-LATHEO antibodyAnti-ORC3L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
