Anti-ONECUT1 antibody (167-292) (STJ114647)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ONECUT1 (167-292) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ONECUT1 |
| Gene ID | 3175 |
| Uniprot ID | HNF6_HUMAN |
| Immunogen Region | 167-292 |
| Immunogen Sequence | PYHKDVAGMGQSLSPLSSSG LGSIHNSQQGLPHYAHPGAA MPTDKMLTPNGFEAHHPAML GRHGEQHLTPTSAGMVPING LPPHHPHAHLNAQGHGQLLG TAREPNPSVTGAQVSNGSNS GQMEEI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human ONECUT1 (NP_004489.1). |
Additional Info
| Tissue Specificity | Highly expressed in liver.lower expression in testis and skin. |
| Function | Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. |
| Protein Name | Hepatocyte Nuclear Factor 6Hnf-6One Cut Domain Family Member 1One Cut Homeobox 1 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hepatocyte Nuclear Factor 6 antibodyAnti-Hnf-6 antibodyAnti-One Cut Domain Family Member 1 antibodyAnti-One Cut Homeobox 1 antibodyAnti-ONECUT1 antibodyAnti-HNF6 antibodyAnti-HNF6A antibody |
Information sourced from Uniprot.org