| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ONECUT1 (167-292) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ONECUT1 |
| Gene ID: |
3175 |
| Uniprot ID: |
HNF6_HUMAN |
| Immunogen Region: |
167-292 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human ONECUT1 (NP_004489.1). |
| Immunogen Sequence: |
PYHKDVAGMGQSLSPLSSSG LGSIHNSQQGLPHYAHPGAA MPTDKMLTPNGFEAHHPAML GRHGEQHLTPTSAGMVPING LPPHHPHAHLNAQGHGQLLG TAREPNPSVTGAQVSNGSNS GQMEEI |
| Tissue Specificity | Highly expressed in liver.lower expression in testis and skin. |
| Function | Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. |
| Protein Name | Hepatocyte Nuclear Factor 6Hnf-6One Cut Domain Family Member 1One Cut Homeobox 1 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210747 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hepatocyte Nuclear Factor 6 antibodyAnti-Hnf-6 antibodyAnti-One Cut Domain Family Member 1 antibodyAnti-One Cut Homeobox 1 antibodyAnti-ONECUT1 antibodyAnti-HNF6 antibodyAnti-HNF6A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
