| Tissue Specificity | Expressed in the brain and the liver. |
| Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. |
| Protein Name | 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial2-Oxoglutarate Dehydrogenase Complex Component E1-LikeOgdc-E1-LikeAlpha-Ketoglutarate Dehydrogenase-Like |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibodyAnti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibodyAnti-Ogdc-E1-Like antibodyAnti-Alpha-Ketoglutarate Dehydrogenase-Like antibodyAnti-OGDHL antibodyAnti-KIAA1290 antibody |
Information sourced from Uniprot.org