• Immunohistochemistry analysis of OGDHL in paraffin-embedded mouse heart using OGDHL Rabbit polyclonal antibody (STJ117670) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of OGDHL in paraffin-embedded human esophageal using OGDHL Rabbit polyclonal antibody (STJ117670) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using OGDHL Rabbit polyclonal antibody (STJ117670) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-OGDHL antibody (1-110) (STJ117670)

SKU:
STJ117670

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-OGDHL (1-110) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OGDHL
Gene ID: 55753
Uniprot ID: OGDHL_HUMAN
Immunogen Region: 1-110
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OGDHL (NP_060715.2).
Immunogen Sequence: MSQLRLLPSRLGVQAARLLA AHDVPVFGWRSRSSGPPATF PSSKGGGGSSYMEEMYFAWL ENPQSVHKSWDSFFREASEE AFSGSAQPRPPSVVHESRSA VSSRTKTSKL
Tissue Specificity Expressed in the brain and the liver.
Function 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis.
Protein Name 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial
2-Oxoglutarate Dehydrogenase Complex Component E1-Like
Ogdc-E1-Like
Alpha-Ketoglutarate Dehydrogenase-Like
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibody
Anti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibody
Anti-Ogdc-E1-Like antibody
Anti-Alpha-Ketoglutarate Dehydrogenase-Like antibody
Anti-OGDHL antibody
Anti-KIAA1290 antibody

Information sourced from Uniprot.org

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