Anti-OGDHL antibody (1-110) (STJ117670)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OGDHL (1-110) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OGDHL |
| Gene ID | 55753 |
| Uniprot ID | OGDHL_HUMAN |
| Immunogen Region | 1-110 |
| Immunogen Sequence | MSQLRLLPSRLGVQAARLLA AHDVPVFGWRSRSSGPPATF PSSKGGGGSSYMEEMYFAWL ENPQSVHKSWDSFFREASEE AFSGSAQPRPPSVVHESRSA VSSRTKTSKL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OGDHL (NP_060715.2). |
Additional Info
| Tissue Specificity | Expressed in the brain and the liver. |
| Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. |
| Protein Name | 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial2-Oxoglutarate Dehydrogenase Complex Component E1-LikeOgdc-E1-LikeAlpha-Ketoglutarate Dehydrogenase-Like |
| Database Links | |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibodyAnti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibodyAnti-Ogdc-E1-Like antibodyAnti-Alpha-Ketoglutarate Dehydrogenase-Like antibodyAnti-OGDHL antibodyAnti-KIAA1290 antibody |
Information sourced from Uniprot.org