Anti-NUDT18 antibody (1-323) (STJ110812)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NUDT18 (1-323) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUDT18 |
| Gene ID | 79873 |
| Uniprot ID | NUD18_HUMAN |
| Immunogen Region | 1-323 |
| Immunogen Sequence | MASEGLAGALASVLAGQGSS VHSCDSAPAGEPPAPVRLRK NVCYVVLAVFLSEQDEVLLI QEAKRECRGSWYLPAGRMEP GETIVEALQREVKEEAGLHC EPETLLSVEERGPSWVRFVF LARPTGGILKTSKEADAESL QAAWYPRTSLPTPLRAHDIL HLVELAAQYRQQARHPLILP QELPCDLVCQRLVATFTSAQ TVWVLVGTVGMPHLPVTACG LDPMEQRGGMKMAVLRLLQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human NUDT18 (NP_079091.3). |
Additional Info
| Function | Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Also hydrolyzes 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools. |
| Protein Name | 8-Oxo-Dgdp Phosphatase Nudt182-Hydroxy-Dadp Phosphatase7 -8-Dihydro-8-Oxoguanine PhosphataseMutt Homolog 3Nucleoside Diphosphate-Linked Moiety X Motif 18Nudix Motif 18 |
| Database Links | Reactome: R-HSA-2393930 Q6ZVK8-1 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-8-Oxo-Dgdp Phosphatase Nudt18 antibodyAnti-2-Hydroxy-Dadp Phosphatase antibodyAnti-7 -8-Dihydro-8-Oxoguanine Phosphatase antibodyAnti-Mutt Homolog 3 antibodyAnti-Nucleoside Diphosphate-Linked Moiety X Motif 18 antibodyAnti-Nudix Motif 18 antibodyAnti-NUDT18 antibodyAnti-MTH3 antibody |
Information sourced from Uniprot.org