Anti-NUB1 antibody (1-100) (STJ11101463)

Name: Anti-NUB1 antibody (1-100) (STJ11101463)
SKU: STJ11101463
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11101463

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Short Description	Rabbit polyclonal NUB1 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	NUB1
Gene ID	51667
Uniprot ID	NUB1_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MAQKKYLQAKLTQFLREDRI QLWKPPYTDENKKVGLALKD LAKQYSDRLECCENEVEKVI EEIRCKAIERGTGNDNYRTT GIATIEVFLPPRLKKDRKNL
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFT140 (NP_001350458.1).

Tissue Specificity	Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
Function	Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Protein Name	Nedd8 Ultimate Buster 1 Negative Regulator Of Ubiquitin-Like Proteins 1 Renal Carcinoma Antigen Ny-Ren-18
Database Links	Reactome: R-HSA-8951664
Cellular Localisation	Nucleus Predominantly Nuclear
Alternative Antibody Names	Anti-Nedd8 Ultimate Buster 1 antibody Anti-Negative Regulator Of Ubiquitin-Like Proteins 1 antibody Anti-Renal Carcinoma Antigen Ny-Ren-18 antibody Anti-NUB1 antibody Anti-NYREN18 antibody

Information sourced from Uniprot.org