| Short Description : | Rabbit polyclonal NSD1 (60-2696) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NSD1 |
| Gene ID: | 64324 |
| Uniprot ID: | NSD1_HUMAN |
| Immunogen Region: | 60-2696 |
| Immunogen Sequence: | AYGQDSPSCYIPLRRLQDLA SMINVEYLNGSADGSESFQD PEKSDSRAQTPIVCTSLSPG GPTALAMKQEPSCNNSPELQ VKVTKTIKNGFLHFENFTCV DDADVDSEMDPEQPVTEDES IEEIFEETQTNATCNYETKS ENGVKVAMGSEQDSTPESRH GAVKSPFLPLAPQTETQKNK QRNEVDGSNEKAALLPAPFS L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-260 of human NSD1 (NP_071900.2). |
| Tissue Specificity | Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung. |
| Function | Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. |
| Protein Name | Histone-Lysine N-Methyltransferase - H3 Lysine-36 SpecificAndrogen Receptor Coactivator 267 Kda ProteinAndrogen Receptor-Associated Protein Of 267 KdaH3-K36-HmtaseLysine N-Methyltransferase 3bNuclear Receptor-Binding Set Domain-Containing Protein 1Nr-Binding Set Domain-Containing Protein |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase - H3 Lysine-36 Specific antibodyAnti-Androgen Receptor Coactivator 267 Kda Protein antibodyAnti-Androgen Receptor-Associated Protein Of 267 Kda antibodyAnti-H3-K36-Hmtase antibodyAnti-Lysine N-Methyltransferase 3b antibodyAnti-Nuclear Receptor-Binding Set Domain-Containing Protein 1 antibodyAnti-Nr-Binding Set Domain-Containing Protein antibodyAnti-NSD1 antibodyAnti-ARA267 antibodyAnti-KMT3B antibody |
Information sourced from Uniprot.org
