| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NSD1 (60-2696) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NSD1 |
| Gene ID: |
64324 |
| Uniprot ID: |
NSD1_HUMAN |
| Immunogen Region: |
60-2696 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-2696 of human NSD1 (NP_071900.2). |
| Immunogen Sequence: |
AYGQDSPSCYIPLRRLQDLA SMINVEYLNGSADGSESFQD PEKSDSRAQTPIVCTSLSPG GPTALAMKQEPSCNNSPELQ VKVTKTIKNGFLHFENFTCV DDADVDSEMDPEQPVTEDES IEEIFEETQTNATCNYETKS ENGVKVAMGSEQDSTPESRH GAVKSPFLPLAPQTETQKNK QRNEVDGSNEKAALLPAPFS L |
| Tissue Specificity | Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung. |
| Function | Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. |
| Protein Name | Histone-Lysine N-Methyltransferase - H3 Lysine-36 SpecificAndrogen Receptor Coactivator 267 Kda ProteinAndrogen Receptor-Associated Protein Of 267 KdaH3-K36-HmtaseLysine N-Methyltransferase 3bNuclear Receptor-Binding Set Domain-Containing Protein 1Nr-Binding Set Domain-Containing Protein |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase - H3 Lysine-36 Specific antibodyAnti-Androgen Receptor Coactivator 267 Kda Protein antibodyAnti-Androgen Receptor-Associated Protein Of 267 Kda antibodyAnti-H3-K36-Hmtase antibodyAnti-Lysine N-Methyltransferase 3b antibodyAnti-Nuclear Receptor-Binding Set Domain-Containing Protein 1 antibodyAnti-Nr-Binding Set Domain-Containing Protein antibodyAnti-NSD1 antibodyAnti-ARA267 antibodyAnti-KMT3B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
