Anti-NSD1 antibody (60-2696) (STJ112022)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NSD1 (60-2696) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NSD1 |
| Gene ID | 64324 |
| Uniprot ID | NSD1_HUMAN |
| Immunogen Region | 60-2696 |
| Immunogen Sequence | AYGQDSPSCYIPLRRLQDLA SMINVEYLNGSADGSESFQD PEKSDSRAQTPIVCTSLSPG GPTALAMKQEPSCNNSPELQ VKVTKTIKNGFLHFENFTCV DDADVDSEMDPEQPVTEDES IEEIFEETQTNATCNYETKS ENGVKVAMGSEQDSTPESRH GAVKSPFLPLAPQTETQKNK QRNEVDGSNEKAALLPAPFS L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-260 of human NSD1 (NP_071900.2). |
Additional Info
| Tissue Specificity | Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung. |
| Function | Histone methyltransferase that dimethylates Lys-36 of histone H3 (H3K36me2). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. |
| Protein Name | Histone-Lysine N-Methyltransferase - H3 Lysine-36 SpecificAndrogen Receptor Coactivator 267 Kda ProteinAndrogen Receptor-Associated Protein Of 267 KdaH3-K36-HmtaseLysine N-Methyltransferase 3bNuclear Receptor-Binding Set Domain-Containing Protein 1Nr-Binding Set Domain-Containing Protein |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase - H3 Lysine-36 Specific antibodyAnti-Androgen Receptor Coactivator 267 Kda Protein antibodyAnti-Androgen Receptor-Associated Protein Of 267 Kda antibodyAnti-H3-K36-Hmtase antibodyAnti-Lysine N-Methyltransferase 3b antibodyAnti-Nuclear Receptor-Binding Set Domain-Containing Protein 1 antibodyAnti-Nr-Binding Set Domain-Containing Protein antibodyAnti-NSD1 antibodyAnti-ARA267 antibodyAnti-KMT3B antibody |
Information sourced from Uniprot.org