| Short Description : | Rabbit polyclonal NRP2 (21-931) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NRP2 |
| Gene ID: | 8828 |
| Uniprot ID: | NRP2_HUMAN |
| Immunogen Region: | 21-931 |
| Immunogen Sequence: | RGQPDPPCGGRLNSKDAGYI TSPGYPQDYPSHQNCEWIVY APEPNQKIVLNFNPHFEIEK HDCKYDFIEIRDGDSESADL LGKHCGNIAPPTIISSGSML YIKFTSDYARQGAGFSLRYE IFKTGSEDCSKNFTSPNGTI ESPGFPEKYPHNLDCTFTIL AKPKMEIILQFLIFDLEHDP LQVGEGDCKYDWLDIWDGI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human NRP2 (NP_957718.1). |
| Function | High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells. |
| Protein Name | Neuropilin-2Vascular Endothelial Cell Growth Factor 165 Receptor 2 |
| Database Links | Reactome: R-HSA-194306Reactome: R-HSA-447038 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform S9: Secreted |
| Alternative Antibody Names | Anti-Neuropilin-2 antibodyAnti-Vascular Endothelial Cell Growth Factor 165 Receptor 2 antibodyAnti-NRP2 antibodyAnti-VEGF165R2 antibody |
Information sourced from Uniprot.org
