Anti-Nrf1 antibody [9E6-H8-B6] (STJA0038222)

SKU:
STJA0038222
$184.23 - $388.47
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Short Description :Mouse monoclonal anti-Nrf1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :9E6-H8-B6
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:2.5 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:NRF1
Gene ID:4899
Uniprot ID:NRF1_HUMAN
Immunogen:Purified recombinant human TCF11/NRF1 protein fragments expressed in E.coli
Tissue Specificity Ubiquitously expressed with strongest expression in skeletal muscle.
Post Translational Modifications Phosphorylation enhances DNA binding.
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Protein Name Nuclear Respiratory Factor 1
Nrf-1
Alpha Palindromic-Binding Protein
Alpha-Pal
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-2151201
Reactome: R-HSA-9841251
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Nuclear Respiratory Factor 1 antibody
Anti-Nrf-1 antibody
Anti-Alpha Palindromic-Binding Protein antibody
Anti-Alpha-Pal antibody
Anti-NRF1 antibody

Information sourced from Uniprot.org