Anti-Nrf1 antibody [9E6-H8-B6] (STJA0038222)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenPurified recombinant human TCF11/NRF1 protein fragments expressed in E.coli
General Information
| Short Description | Mouse monoclonal anti-Nrf1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 9E6-H8-B6 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 2.5 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NRF1 |
| Gene ID | 4899 |
| Uniprot ID | NRF1_HUMAN |
| Immunogen | Purified recombinant human TCF11/NRF1 protein fragments expressed in E.coli |
Additional Info
| Tissue Specificity | Ubiquitously expressed with strongest expression in skeletal muscle. |
| Post Translational Modifications | Phosphorylation enhances DNA binding. |
| Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
| Protein Name | Nuclear Respiratory Factor 1Nrf-1Alpha Palindromic-Binding ProteinAlpha-Pal |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2151201Reactome: R-HSA-9841251 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Respiratory Factor 1 antibodyAnti-Nrf-1 antibodyAnti-Alpha Palindromic-Binding Protein antibodyAnti-Alpha-Pal antibodyAnti-NRF1 antibody |
Information sourced from Uniprot.org