| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NR0B1 (1-260) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NR0B1 |
| Gene ID: |
190 |
| Uniprot ID: |
NR0B1_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human NR0B1 (NP_000466.2). |
| Immunogen Sequence: |
MAGENHQWQGSILYNMLMSA KQTRAAPEAPETRLVDQCWG CSCGDEPGVGREGLLGGRNV ALLYRCCFCGKDHPRQGSIL YSMLTSAKQTYAAPKAPEAT LGPCWGCSCGSDPGVGRAGL PGGRPVALLYRCCFCGEDHP RQGSILYSLLTSSKQTHVAP AAPEARPGGAWWDRSYFAQR PGGKEALPGGRATALLYRCC FCGEDHPQQGSTLYCVPTST NQAQAAPEERPRAPWWDTS |
| Function | Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. |
| Protein Name | Nuclear Receptor Subfamily 0 Group B Member 1Dss-Ahc Critical Region On The X Chromosome Protein 1Nuclear Receptor Dax-1 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And NucleusHomodimers Exits In The Cytoplasm And In The Nucleus |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 0 Group B Member 1 antibodyAnti-Dss-Ahc Critical Region On The X Chromosome Protein 1 antibodyAnti-Nuclear Receptor Dax-1 antibodyAnti-NR0B1 antibodyAnti-AHC antibodyAnti-DAX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
