| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-N-acetylneuraminate lyase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NPL |
| Gene ID: |
80896 |
| Uniprot ID: |
NPL_HUMAN |
| Specificity: |
This antibody detects endogenous levels of NPL at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human NPL |
| Function | Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (Probable). |
| Protein Name | N-Acetylneuraminate LyaseNalaseN-Acetylneuraminate Pyruvate-LyaseN-Acetylneuraminic Acid AldolaseSialate LyaseSialate-Pyruvate LyaseSialic Acid AldolaseSialic Acid Lyase |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-N-Acetylneuraminate Lyase antibodyAnti-Nalase antibodyAnti-N-Acetylneuraminate Pyruvate-Lyase antibodyAnti-N-Acetylneuraminic Acid Aldolase antibodyAnti-Sialate Lyase antibodyAnti-Sialate-Pyruvate Lyase antibodyAnti-Sialic Acid Aldolase antibodyAnti-Sialic Acid Lyase antibodyAnti-NPL antibodyAnti-C1orf13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
