Anti-NPL antibody (STJA0009408)

SKU:
STJA0009408

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-N-acetylneuraminate lyase is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NPL
Gene ID: 80896
Uniprot ID: NPL_HUMAN
Specificity: This antibody detects endogenous levels of NPL at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human NPL
Function Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (Probable).
Protein Name N-Acetylneuraminate Lyase
Nalase
N-Acetylneuraminate Pyruvate-Lyase
N-Acetylneuraminic Acid Aldolase
Sialate Lyase
Sialate-Pyruvate Lyase
Sialic Acid Aldolase
Sialic Acid Lyase
Database Links Reactome: R-HSA-4085001
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-N-Acetylneuraminate Lyase antibody
Anti-Nalase antibody
Anti-N-Acetylneuraminate Pyruvate-Lyase antibody
Anti-N-Acetylneuraminic Acid Aldolase antibody
Anti-Sialate Lyase antibody
Anti-Sialate-Pyruvate Lyase antibody
Anti-Sialic Acid Aldolase antibody
Anti-Sialic Acid Lyase antibody
Anti-NPL antibody
Anti-C1orf13 antibody

Information sourced from Uniprot.org

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