Anti-nNOS antibody (STJ13100503)

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STJ13100503-100
€387.00
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Short Description :Guinea Pig polyclonal anti-nNOS for use in IHC and WB in Human, Mouse, Rat and Marmoset samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Guinea Pig
Reactivity:Human/Mouse/Rat/Marmoset
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Conjugation:Unconjugated
Purification:Affinity purification
Dilution Range:IHC, WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:Nos1
Gene ID:24598
Uniprot ID:NOS1_RAT
Immunogen:A synthetic peptide from human nNOS conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with rat's sequence.
Specificity:Specific for nNOS
Post Translational Modifications Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
Protein Name Nitric Oxide Synthase 1
Constitutive Nos
Nc-Nos
Nos Type I
Neuronal Nos
N-Nos
Nnos
Nitric Oxide Synthase - Brain
Bnos
Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links Reactome: R-RNO-1222556
Reactome: -RNO-392154
Reactome: -RNO-5578775
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cell Projection
Dendritic Spine
In Skeletal Muscle
It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex
In Neurons
Enriched In Dendritic Spines
Alternative Antibody Names Anti-Nitric Oxide Synthase 1 antibody
Anti-Constitutive Nos antibody
Anti-Nc-Nos antibody
Anti-Nos Type I antibody
Anti-Neuronal Nos antibody
Anti-N-Nos antibody
Anti-Nnos antibody
Anti-Nitric Oxide Synthase - Brain antibody
Anti-Bnos antibody
Anti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibody
Anti-Nos1 antibody
Anti-Bnos antibody

Information sourced from Uniprot.org