Anti-nNOS antibody [SRM13521] (STJ11108251)

SKU:
STJ11108251
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Host: Rabbit
Applications: WB/IF/ICC/IF-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM13521
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB, 1:500-1:1000
IF/ICC, 1:50-1:200
IF-P, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NOS1
Gene ID: 4842
Uniprot ID: NOS1_HUMAN
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Sequence: Human
Post Translational Modifications Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Protein Name Nitric Oxide Synthase 1
Constitutive Nos
Nc-Nos
Nos Type I
Neuronal Nos
N-Nos
Nnos
Nitric Oxide Synthase - Brain
Bnos
Peptidyl-Cysteine S-Nitrosylase Nos1
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-392154
Reactome: R-HSA-5578775
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cell Projection
Dendritic Spine
In Skeletal Muscle
It Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein Complex
In Neurons
Enriched In Dendritic Spines
Alternative Antibody Names Anti-Nitric Oxide Synthase 1 antibody
Anti-Constitutive Nos antibody
Anti-Nc-Nos antibody
Anti-Nos Type I antibody
Anti-Neuronal Nos antibody
Anti-N-Nos antibody
Anti-Nnos antibody
Anti-Nitric Oxide Synthase - Brain antibody
Anti-Bnos antibody
Anti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibody
Anti-NOS1 antibody

Information sourced from Uniprot.org