Anti-nNOS antibody [SRM13521] (STJ11108251)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Nitric Oxide Synthase 1 antibody for use in WB, IF, ICC, IF-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13521 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:500-1:1000IF/ICC, 1:50-1:200IF-P, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NOS1 |
| Gene ID | 4842 |
| Uniprot ID | NOS1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Post Translational Modifications | Ubiquitinated.mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro). |
| Function | Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. |
| Protein Name | Nitric Oxide Synthase 1Constitutive NosNc-NosNos Type INeuronal NosN-NosNnosNitric Oxide Synthase - BrainBnosPeptidyl-Cysteine S-Nitrosylase Nos1 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-392154Reactome: R-HSA-5578775 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCell ProjectionDendritic SpineIn Skeletal MuscleIt Is Localized Beneath The Sarcolemma Of Fast-Twitch Muscle Fiber By Associating With The Dystrophin Glycoprotein ComplexIn NeuronsEnriched In Dendritic Spines |
| Alternative Antibody Names | Anti-Nitric Oxide Synthase 1 antibodyAnti-Constitutive Nos antibodyAnti-Nc-Nos antibodyAnti-Nos Type I antibodyAnti-Neuronal Nos antibodyAnti-N-Nos antibodyAnti-Nnos antibodyAnti-Nitric Oxide Synthase - Brain antibodyAnti-Bnos antibodyAnti-Peptidyl-Cysteine S-Nitrosylase Nos1 antibodyAnti-NOS1 antibody |
Information sourced from Uniprot.org