Anti-NME7 antibody (152-202 aa) (STJ195115)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NDK7 at the amino acid range 152-202
General Information
| Short Description | Rabbit polyclonal anti-Nucleoside diphosphate kinase 7 (152-202 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NME7 |
| Gene ID | 29922 |
| Uniprot ID | NDK7_HUMAN |
| Immunogen | Synthesized peptide derived from the human NDK7 at the amino acid range 152-202 |
| Immunogen Region | 152-202 aa |
| Specificity | This antibody detects endogenous levels of NDK7 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Undergoes autophosphorylation. |
| Function | Possesses an intrinsic kinase activity. Displays 3'-5' exonuclease activity with a preference for single-stranded DNA. Does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner. Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. |
| Protein Name | Nucleoside Diphosphate Kinase Homolog 7Ndk 7Ndp Kinase Homolog 73'-5' Exonuclease Nme7Protein Kinase Nme7Nm23-H7 |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusSpindleCilium AxonemeFlagellum AxonemeCell ProjectionCiliumLocalizes To Centrosomes Through Its Assembly Into Gamma-Tubulin Ring ComplexThe Centrosomal Content Of Nme7 Varies During The Cell CycleBeing Highest In Mitosis And Lowest In Early G1 |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Kinase Homolog 7 antibodyAnti-Ndk 7 antibodyAnti-Ndp Kinase Homolog 7 antibodyAnti-3'-5' Exonuclease Nme7 antibodyAnti-Protein Kinase Nme7 antibodyAnti-Nm23-H7 antibodyAnti-NME7 antibody |
Information sourced from Uniprot.org