| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Nucleoside diphosphate kinase 7 (152-202 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NME7 |
| Gene ID: |
29922 |
| Uniprot ID: |
NDK7_HUMAN |
| Immunogen Region: |
152-202 aa |
| Specificity: |
This antibody detects endogenous levels of NDK7 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human NDK7 at the amino acid range 152-202 |
| Post Translational Modifications | Undergoes autophosphorylation. |
| Function | Possesses an intrinsic kinase activity. Displays 3'-5' exonuclease activity with a preference for single-stranded DNA. Does not seem to have nucleoside diphosphate kinase activity. Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner. Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. |
| Protein Name | Nucleoside Diphosphate Kinase Homolog 7Ndk 7Ndp Kinase Homolog 73'-5' Exonuclease Nme7Protein Kinase Nme7Nm23-H7 |
| Database Links | Reactome: R-HSA-380270Reactome: R-HSA-380320 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusSpindleCilium AxonemeFlagellum AxonemeLocalizes To Centrosomes Through Its Assembly Into Gamma-Tubulin Ring ComplexThe Centrosomal Content Of Nme7 Varies During The Cell CycleBeing Highest In Mitosis And Lowest In Early G1 |
| Alternative Antibody Names | Anti-Nucleoside Diphosphate Kinase Homolog 7 antibodyAnti-Ndk 7 antibodyAnti-Ndp Kinase Homolog 7 antibodyAnti-3'-5' Exonuclease Nme7 antibodyAnti-Protein Kinase Nme7 antibodyAnti-Nm23-H7 antibodyAnti-NME7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
