Anti-NKX6.1 antibody (STJA0038016)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human NKX6.1
General Information
| Short Description | Rabbit monoclonal anti-NKX6.1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NKX6-1 |
| Gene ID | 4825 |
| Uniprot ID | NKX61_HUMAN |
| Immunogen | Recombinant protein of human NKX6.1 |
Additional Info
| Tissue Specificity | Pancreatic beta cells. |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-6.1 antibodyAnti-Homeobox Protein Nk-6 Homolog A antibodyAnti-NKX6-1 antibodyAnti-NKX6A antibody |
Information sourced from Uniprot.org