| Tissue Specificity | Pancreatic beta cells. |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-6.1 antibodyAnti-Homeobox Protein Nk-6 Homolog A antibodyAnti-NKX6-1 antibodyAnti-NKX6A antibody |
Information sourced from Uniprot.org
