• Western blot with Anti-NKG2D Antibody (STJ501924) of THP cell at 1: dilution in buffer.

Anti-NKG2D antibody (180-230) (STJ501924)

SKU:
STJ501924-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Bovine/Human/Monkey/Panda
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NKG2D (180-230) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Klrk1
Gene ID: 24934
Uniprot ID: NKG2D_RAT
Immunogen Region: 180-230
Immunogen: Synthetic peptide taken within amino acid region 180-230 on rat NKG2D protein.
Tissue Specificity Expressed by natural killer cells and by resting thoracic duct CD4+ and CD8+ T-cells, but not by thymocytes or other hemopoietic cells. Expressed by DC cells.
Function Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins.
Protein Name Nkg2-D Type Ii Integral Membrane Protein
Killer Cell Lectin-Like Receptor Subfamily K Member 1
Nk Cell Receptor D
Nk Lectin-Like Receptor
Nkllr
Nkg2-D-Activating Nk Receptor
Nkr-P2
Cd Antigen Cd314
Database Links Reactome: R-RNO-198933
Reactome: -RNO-2424491
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Colocalized With Hcst On The Cell Surface
Alternative Antibody Names Anti-Nkg2-D Type Ii Integral Membrane Protein antibody
Anti-Killer Cell Lectin-Like Receptor Subfamily K Member 1 antibody
Anti-Nk Cell Receptor D antibody
Anti-Nk Lectin-Like Receptor antibody
Anti-Nkllr antibody
Anti-Nkg2-D-Activating Nk Receptor antibody
Anti-Nkr-P2 antibody
Anti-Cd Antigen Cd314 antibody
Anti-Klrk1 antibody
Anti-Nkg2d antibody
Anti-Nkrp2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance