Anti-NEXN antibody (516-675) (STJ115102)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NEXN (516-675) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEXN |
| Gene ID | 91624 |
| Uniprot ID | NEXN_HUMAN |
| Immunogen Region | 516-675 |
| Immunogen Sequence | RFEQMAKAREEEEQRRIEEQ KLLRMQFEQREIDAALQKKR EEEEEEEGSIMNGSTAEDEE QTRSGAPWFKKPLKNTSVVD SEPVRFTVKVTGEPKPEITW WFEGEILQDGEDYQYIERGE TYCLYLPETFPEDGGEYMCK AVNNKGSAASTCILTIESKN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 516-675 of human NEXN (NP_653174.3). |
Additional Info
| Tissue Specificity | Abundantly expressed in heart and skeletal muscle, and at lower levels in placenta, lung, liver and pancreas. Also expressed in HeLaS3 and MOLT-4 cell lines. |
| Function | Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity. |
| Protein Name | NexilinF-Actin-Binding ProteinNelin |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionAdherens JunctionMyofibrilSarcomereZ LineLocalizes To The Cell-Matrix AjNot Found At The Cell-Cell Aj |
| Alternative Antibody Names | Anti-Nexilin antibodyAnti-F-Actin-Binding Protein antibodyAnti-Nelin antibodyAnti-NEXN antibody |
Information sourced from Uniprot.org