| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NEXN (516-675) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NEXN |
| Gene ID: |
91624 |
| Uniprot ID: |
NEXN_HUMAN |
| Immunogen Region: |
516-675 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 516-675 of human NEXN (NP_653174.3). |
| Immunogen Sequence: |
RFEQMAKAREEEEQRRIEEQ KLLRMQFEQREIDAALQKKR EEEEEEEGSIMNGSTAEDEE QTRSGAPWFKKPLKNTSVVD SEPVRFTVKVTGEPKPEITW WFEGEILQDGEDYQYIERGE TYCLYLPETFPEDGGEYMCK AVNNKGSAASTCILTIESKN |
| Tissue Specificity | Abundantly expressed in heart and skeletal muscle, and at lower levels in placenta, lung, liver and pancreas. Also expressed in HeLaS3 and MOLT-4 cell lines. |
| Function | Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity. |
| Protein Name | NexilinF-Actin-Binding ProteinNelin |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionAdherens JunctionMyofibrilSarcomereZ LineLocalizes To The Cell-Matrix AjNot Found At The Cell-Cell Aj |
| Alternative Antibody Names | Anti-Nexilin antibodyAnti-F-Actin-Binding Protein antibodyAnti-Nelin antibodyAnti-NEXN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
