Anti-Neurotrophin-4/5 antibody (STJA0041023)
SPECIFICATIONS
ClonalityPolyclonal
HostSheep
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human NT4
General Information
| Short Description | Sheep polyclonal anti-Neurotrophin-4/5 for use in ELISA, IHC-F, Neut and WB in Human, Mouse, Non-Human Primates and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC-F/Neut/WB |
| Host | Sheep |
| Reactivity | Human/Mouse/Non-Human Primates/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG |
| Dilution Range | WB 2-10 µg/mLIHC 2-10 µg/mL |
| Formulation | Lyophilized from a solution containing PBS pH 7.4 |
| Storage Instruction | Spin vial briefly before opening. Reconstitute in 500 µL sterile-filtered 1X PBS, pH 7.2-7.6. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacteri |
Target Information
| Gene Symbol | NTF4 |
| Gene ID | 4909 |
| Uniprot ID | NTF4_HUMAN |
| Immunogen | Recombinant human NT4 |
| Immunogen Sequence | Human |
| Specificity | Less than 1% cross-reactivity against NGF, recombinant human BDNF and 5% to NT3 has been shown by dot blot. Known to react with NT4 from rat and human, mouse and monkey. |
Additional Info
| Tissue Specificity | Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. |
| Function | Target-derived survival factor for peripheral sensory sympathetic neurons. May promote ameloblast differentiation and subsequent reduction in proliferation of ameloblasts. |
| Protein Name | Neurotrophin-4Nt-4Neurotrophin-5Nt-5Neutrophic Factor 4 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-6811558Reactome: R-HSA-9026357Reactome: R-HSA-9026519Reactome: R-HSA-9026527Reactome: R-HSA-9028335Reactome: R-HSA-9028731 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neurotrophin-4 antibodyAnti-Nt-4 antibodyAnti-Neurotrophin-5 antibodyAnti-Nt-5 antibodyAnti-Neutrophic Factor 4 antibodyAnti-NTF4 antibodyAnti-NTF5 antibody |
Information sourced from Uniprot.org