Anti-Neurotrophin-4/5 antibody (STJA0041023)

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STJA0041023-500
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Short Description :Sheep polyclonal anti-Neurotrophin-4/5 for use in ELISA, IHC-F, Neut and WB in Human, Mouse, Non-Human Primates and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/IHC-F/Neut/WB
Host:Sheep
Reactivity:Human/Mouse/Non-Human Primates/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG
Dilution Range:WB 2-10 µg/mL
IHC 2-10 µg/mL
Formulation:Lyophilized from a solution containing PBS pH 7.4
Storage Instruction:Spin vial briefly before opening. Reconstitute in 500 µL sterile-filtered 1X PBS, pH 7.2-7.6. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at-20°C for a higher stability, and at 2-8°C with an appropriate antibacteri
Gene Symbol:NTF4
Gene ID:4909
Uniprot ID:NTF4_HUMAN
Immunogen:Recombinant human NT4
Immunogen Sequence:Human
Specificity:Less than 1% cross-reactivity against NGF, recombinant human BDNF and 5% to NT3 has been shown by dot blot. Known to react with NT4 from rat and human, mouse and monkey.
Tissue Specificity Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
Function Target-derived survival factor for peripheral sensory sympathetic neurons. May promote ameloblast differentiation and subsequent reduction in proliferation of ameloblasts.
Protein Name Neurotrophin-4
Nt-4
Neurotrophin-5
Nt-5
Neutrophic Factor 4
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-6811558
Reactome: R-HSA-9026357
Reactome: R-HSA-9026519
Reactome: R-HSA-9026527
Reactome: R-HSA-9028335
Reactome: R-HSA-9028731
Cellular Localisation Secreted
Alternative Antibody Names Anti-Neurotrophin-4 antibody
Anti-Nt-4 antibody
Anti-Neurotrophin-5 antibody
Anti-Nt-5 antibody
Anti-Neutrophic Factor 4 antibody
Anti-NTF4 antibody
Anti-NTF5 antibody

Information sourced from Uniprot.org